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Fact checked by Robert Iafelice, MS, RD, LDN
FACT CHECKEDOver the past decade, the field of nootropics has entered the mainstream supplement market, mirroring the increased memory and cognitive function demands that our fast-paced society puts upon us.
NooCube and VyvaMind are a couple of popular nootropic supplements, both promising to unlock new heights of cognitive ability. But which is better?
In this Noocube vs. Vyvamind review, we put them head to head to find out which comes out on top.
Table Of Contents:
Vyvamind is a nootropic supplement that includes stimulant ingredients. It is designed to deliver an instant brain boost and provide a range of cognitive health benefits, including improved overall brain health, memory, focus, mental clarity, stress management, and anxiety reduction.
Vyvamind contains the following ingredients:
Citicoline
Caffeine
Theanine
Tyrosine
Vitamin B6
Vitamin B12
The inclusion of caffeine makes Vyvamind a stimulant-based nootropic. The Vyvamind dosage is one capsule per day. A one-month supply consisting of 60 capsules costs $74.99. It is only available from the official website.
SAP Nutraceuticals, an established supplement company with a reputation for quality products and good service, manufactures Vyvamind.
The company claims its product works through three mechanisms to provide cognitive benefits:
It improves blood flow to the brain to provide more oxygen and nutrients.
Its ingredients stimulate the production of dopamine and serotonin, both mood enhancers.
Vyvamind is claimed to enhance neuroplasticity, which is the brain's ability to adjust to new circumstances.
NooCube is a brain-boosting supplement that, unlike Vyvamind, is stimulant-free and contains no caffeine.
It contains several more ingredients than Vyvamind, but not as many have solid research to support their inclusion. NooCube is manufactured by Wolfson Brands (UK) Ltd, which produces a range of popular health and fitness supplements.
NooCube nootropic is designed to improve cognitive function, perception, decision-making, memory, focus, and learning while offsetting mental fatigue. Rather than providing an immediate brain boost as VyvaMind promises, NooCube promises to deliver more of a long-lasting cognitive benefit.
Wolfson Brands is always striving to improve its products. NooCube was recently updated, with Alpha GPC, oat straw extract, biotin, and magnesium stearate replaced by VitaCholine, Panax Ginseng, D-Biotin, and vegetable magnesium stearate.
The dosage for NooCube is two capsules per day. A one-month supply can be purchased from the official website for $64.99.
Let's now dig down on what you get in each two-capsule serving of Vyvamind:
Caffeine: Caffeine has stimulant properties that provide a jolt of energy and alertness. It does this by blocking the brain's adenosine receptors. There are 75 mg of caffeine anhydrous in every serving of Vyvamind. That's a little less than you'd get in a regular cup of coffee and is pretty low for a nootropic stimulant.
Theanine: Theanine provides a concentrated state of relaxation when combined with coffee, lessening the jittery effects of the latter while promoting focus and mental clarity. There is 150 mg of theanine in Vyvamind. That aligns with the amounts used in research studies and corresponds to the typical 2:1 ratio with caffeine.
Tyrosine: The amino acid tyrosine helps calm the mind in stressful situations. It does this by encouraging the production of dopamine and norepinephrine, promoting concentration and mental stamina. Vyvamind contains 300 mg of tyrosine, keeping with the clinically used dosages for improved cognitive functions of between 100 and 500 mg.
Vitamin B6: Vitamin B6 is needed for neurotransmitter production. As such, it assists in maintaining the brain's communication network. There are 2.5 mg of Vitamin B6 in each serving of Vyvamind.
Vitamin B12: This vitamin assists in creating the myelin sheaths, which protect nerve cells and enhance brain cell communication. Each capsule of Vyvamind contains 50 mcg of Vitamin B12.
There are 12 NooCube ingredients. Here's an overview of what each one does:
VitaCholine: VitaCholine is an advanced form of choline that helps make acetylcholine, which is needed for cognitive function. There are 250 mg of choline in NooCube, which is on the low side of the 250-500 mg typically used in nootropic supplements for comprehensive cognitive support.
Resveratrol: This antioxidant may help protect brain cells from oxidative stress. You get 14.3 mg of resveratrol in each serving of NooCube, which is considerably down from the typical dosage for cognitive benefits, which ranges between 100 and 250 mg.
Lutemax 2020: A combination of lutein and zeaxanthin, Lutemax 2020 is linked to eye health with limited evidence to support cognitive benefits. There are 20 mg of Lutemax 2020 in NooCube. We don't know the specific doses of lutein and zeaxanthin, but the recommended supplement doses for lutein are 6 to 20 mg daily and 4 to 6 mg daily for zeaxanthin.
L-Theanine: L-Theanine promotes relaxation and focus with no drowsy effects. There are 100 mg of theanine in every serving of NooCube. That compares to 150 mg for Vyvamind.
Bacopa Monnieri: This herbal extract is claimed to boost memory, mood, and brain function. There are 250 mg of bacopa monnieri in NooCube, with a 12:1 ratio and a guaranteed 20% bacoside (the active ingredient) content. This is a little lower than the typically used amount in cognitive enhancement supplements, which is between 300 and 450 mg daily.
Panax Ginseng: Panax Ginseng is an adaptogen that can help reduce stress and anxiety. You get 20 mg of Panax Ginseng in Noocube. That is well down on the research-supported range of 100 to 400 mg per day.
L-Tyrosine: This amino acid helps to produce neurotransmitters that improve attention and cognitive function. There are 250 mg of tyrosine in every serving of NooCube, which is a little lower than the 300 mg used in Vyvamind.
Cat's Claw: Cat's Claw possibly has antioxidant and cognitive-supporting effects. You get 175 mg of Cat's Claw in each single capsule serving of NooCube. That falls short of the typical nootropic supplement range of between 250 and 500 mg.
Vitamin B1: Vitamin B1 is essential for healthy metabolism. Its brain-boosting ability is less certain. There is 1.1 mg of Vitamin B1 in NooCube.
Vitamin B12: Vitamin B12 promotes the health of nerves and may indirectly boost cognitive ability. You get 2.5 mcg of Vitamin B12 in NooCube. That is significantly less than the 50 mcg in Vyvamind.
D-Biotin: D-Biotin is vital for metabolic activities and may tangentially promote brain health. There are 50 mcg of d-biotin in each serving of NooCube. That's on the low side of the recommended nootropic supplement range of between 50 and 300 mg daily.
Pterostilbine: Plants like blueberries contain a substance called pterostilbene, which may have neuroprotective properties. You get 140 mcg of pterostilbene in NooCube, which is in line with the typical 50-250 mg range.
Vyvamind and NooCube share the following key ingredients:
Theanine
Tyrosine
Vitamin B12
Both of these supplements are designed to enhance focus and memory, improve cognitive performance, and offset cognitive decline. They both contain only natural herbally-based ingredients, vitamins, and amino acids. They are both considered to be safe for the vast majority of people when taken at the recommended dosages.
The critical difference between these two supplements is that Vyvamind contains caffeine, making it a stimulant-based nootropic. There is no caffeine or other stimulants in NooCube.
The effect of this difference is that the effects of Vyvamind will be felt more quickly, with a mental energy and focus boost clicking in almost immediately. In contrast, the effects of NooCube may take several days to be felt as the ingredients build up in the body. People sensitive to caffeine may get a jittery reaction and experience an energy crash a few hours after taking Vyvamind.
Due to its ability to provide you with a quick energy and alertness boost, Vyvamind is better suited for people who need a pick-me-up, are pulling an all-nighter to study for an exam, or otherwise want an immediate brain boost. The NooCube supplement may be a better option for those who want to offset age-related cognitive deficits but are not expecting an immediate effect.
There are more than double the ingredients in NooCube compared to Vyvamind. However, some of these ingredients have quite dubious backing to support their inclusion in a nootropic supplement. The ingredients in Vyvamind are also more effectively dosed than those in NooCube. As a result, it is fair to say that Vyvamind achieves more with less.
There are also slightly different areas of focus in the two ingredient profiles. While both aim to improve general cognition and memory, Vyvamind includes ingredients directly affecting neurotransmitter production and activity. NooCube has compounds that may help offset the effects of oxidative stress and have stress-reducing properties.
Despite being considered safe for most people, Vyvamind and NooCube may cause uncomfortable side effects. The main difference between them is caffeine's potential side effects in people who are insensitive to it. Vyvamind side effects may include:
A jittery, wired feeling
An energy crash about 90 minutes after taking the supplement
Increased heart rate
Sleep disruption, especially if you take it within a couple of hours of going to bed
Gastrointestinal distress, including gas, belching, constipation, or diarrhea
Possible side effects of NooCube include:
Headache
Gastrointestinal problems similar to those with Vyvamind
Insomnia
The best option between Vyvamind and NooCube for you depends on your objectives for taking a nootropic supplement.
Groups Who Would Benefit from Stimulant-Based Nootropics (Like VyvaMind):
Those needing immediate cognitive improvement for specific tasks or circumstances that call for extreme attentiveness and focus.
People in high-stress, quick-paced occupations that demand constant attention and mental agility.
Those trying to overcome momentary exhaustion or sleep deprivation, such as students preparing for exams or workers who put in long hours.
People who can sustain enhanced alertness without experiencing side effects like jitters or insomnia and are not sensitive to stimulants like coffee.
Those who perform challenging short-term cognitive tasks, such as presentations, public speaking, or critical decision-making.
Vyvamind [NSV-313] is a natural fast-acting, broad spectrum over the counter neurostimulant for high-performance adults. Specifically designed for use in mentally demanding situations...
Groups Who Would Benefit from Long-Lasting, Slower-Acting Nootropics (like NooCube):
Those who want constant cognitive support for their daily mental activities without experiencing sharp energy drops.
People who choose long-term brain health, memory improvement, and mental clarity over short-term cognitive energy spikes.
Those who react negatively to stimulants are prone to suffering adverse side effects like jitteriness or a heightened heart rate.
Older persons who want to promote memory retention and cognitive performance as a component of healthy aging.
People responsible for tasks that need sustained focus over time, such as analytical or creative initiatives.
Remember that particular responses to nootropics can differ, and whether a person is suitable for a given sort of nootropic depends on things like general health, lifestyle, tolerance to stimulants, and particular objectives.
NooCube works alongside your daily routine as a functional nootropic — allowing you to get more accomplished in a 24-hour period without feeling overwhelmed by...
From our comparison, it's clear that the two nootropic supplements, Vyvamind and NooCube, provide different methods for increasing cognitive and mental performance throughout.
Given that Vyvamind's formula is stimulant-based and produces short bursts of attention and alertness, it is appropriate for people looking to sharpen their cognitive abilities while doing complex tasks. In contrast, NooCube's caffeine-free formula is designed to meet the needs of those who want sustained cognitive support without the danger of energy crashes or stimulant-related adverse effects.
Although NooCube has a longer ingredient list, Vyvamind's ingredients are better dosed and have strong research backing. Your unique requirements, preferences, and sensitivities will ultimately determine whether you choose Vyvamind or NooCube.
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